Gaining weight after switching to a new antiretroviral combination is common, especially after switching from efavirenz or the older formulation of tenofovir, but most weight gain is modest and occurs in the first year after switching, a review of 12 large clinical trials shows. The results suggest that some older antiretrovirals may have a weight-suppressive… Read More »
Most patients in the COHERE group were either gay and bisexual men (about 60%) or heterosexual (30%): only 2.7% were injecting drug users. Ethnicity was not recorded in 42% of people, was white in 41% and black in 12%. Their average age was 39 when they started ART, with an average baseline CD4 count of… Read More »
The European Pregnancy and Paediatric HIV Cohort Collaboration includes data from 24,963 pregnancies ending in singleton live births between 2002 and 2015. Cohorts in Belgium, Denmark, Germany, Ireland, Italy, the Netherlands, Poland, Romania, Spain, Sweden, Switzerland, Thailand, Ukraine and the United Kingdom provided data. In 1200 pregnancies (4.8%), the mother received efavirenz at the time… Read More »